Items 1 to 10 of about 27220
1. Santos VC, Anjos KF, Boery RN, Moreira RM, Cruz DP, Boery EN: Hospitalization and hospital mortality of elderly people with mental and behavioral disorders in Brazil, 2008-2014. Epidemiol Serv Saude; 2017 Jan-Mar;26(1):39-49

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Hospitalization and hospital mortality of elderly people with mental and behavioral disorders in Brazil, 2008-2014.
  • [Transliterated title] Internação e mortalidade hospitalar de idosos por transtornos mentais e comportamentais no Brasil, 2008-2014.
  • OBJECTIVE:: to analyze the evolution of hospitalizations and hospital mortality of elderly people with mental and behavioral disorders in Brazil, from 2008 to 2014.
  • RESULTS:: during the studied period, 139,941 hospitalizations and 2,962 deaths were recorded; the hospitalization coefficient for mental and behavioral disorders decreased in Brazil, from 122.3 to 84.2 per 100 thousand inhabitants (-0.14%; 95%CI -0.25;-0.03), and its macroregions, except the South, which presented stationary trend (0.08%; 95%CI -0.11;0.27); the hospital mortality coefficients in Brazil, in 2008 and 2014, were, respectively, 1.73 and 2.38 per 100 thousand inhabitants; dementia was the main diagnosis in hospitalizations that registered deaths (32.3%).

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  • (PMID = 28226007.001).
  • [ISSN] 2237-9614
  • [Journal-full-title] Epidemiologia e servicos de saude : revista do Sistema Unico de Saude do Brasil
  • [ISO-abbreviation] Epidemiol Serv Saude
  • [Language] por; eng
  • [Publication-type] Journal Article
  • [Publication-country] Brazil
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2. Warren DK, Nickel KB, Wallace AE, Mines D, Tian F, Symons WJ, Fraser VJ, Olsen MA: Risk Factors for Surgical Site Infection After Cholecystectomy. Open Forum Infect Dis; 2017;4(2):ofx036

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Independent risk factors for SSI included male gender, preoperative chronic anemia, diabetes, drug abuse, malnutrition/weight loss, obesity, smoking-related diseases, previous <i>Staphylococcus aureus</i> infection, laparoscopic approach with acute cholecystitis/obstruction (hazards ratio [HR], 1.58; 95% confidence interval [CI], 1.27-1.96), open approach with (HR, 4.29; 95% CI, 2.45-7.52) or without acute cholecystitis/obstruction (HR, 4.04; 95% CI, 1.96-8.34), conversion to open approach with (HR, 4.71; 95% CI, 2.74-8.10) or without acute cholecystitis/obstruction (HR, 7.11; 95% CI, 3.87-13.08), bile duct exploration, postoperative chronic anemia, and postoperative pneumonia or urinary tract infection.

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  • (PMID = 28491887.001).
  • [Journal-full-title] Open forum infectious diseases
  • [ISO-abbreviation] Open Forum Infect Dis
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; administrative health claims data / cholecystectomy / risk factors / surgical site infection.
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3. Gopal Rao G, Nartey G, McAree T, O'Reilly A, Hiles S, Lee T, Wallace S, Batura R, Khanna P, Abbas H, Tilsed C, Nicholl R, Lamagni T, Bassett P: Outcome of a screening programme for the prevention of neonatal invasive early-onset group B Streptococcus infection in a UK maternity unit: an observational study. BMJ Open; 2017 Apr 18;7(4):e014634

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • PARTICIPANTS: Women who gave birth between March 2014 and December 2015 at Northwick Park Hospital.
  • Screening programme was first introduced in hospital (March 2014) and then in community (August 2014).
  • Screening rate improved progressively from 42% in 2014 to 75% in 2015.
  • All strains were susceptible to penicillin but 11.3% (206/1822) were resistant to clindamycin.
  • Early onset GBS rate fell from 0.99/1000 live births (25/25276) in the prescreening period to 0.33/1000 in the screening period (Rate Ratio=0.33; p=0.08).

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  • [Copyright] Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
  • (PMID = 28420662.001).
  • [ISSN] 2044-6055
  • [Journal-full-title] BMJ open
  • [ISO-abbreviation] BMJ Open
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; Group B Streptococcus / early onset infection / neonates / screening
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4. Steinhagen-Thiessen E, Stroes E, Soran H, Johnson C, Moulin P, Iotti G, Zibellini M, Ossenkoppele B, Dippel M, Averna MR, GENIALL Investigators: The role of registries in rare genetic lipid disorders: Review and introduction of the first global registry in lipoprotein lipase deficiency. Atherosclerosis; 2016 Aug 21;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • Alipogene tiparvovec (Glybera<sup>®</sup>) is the first gene therapy to receive Marketing Authorization in the European Union; GENIALL (GENetherapy In the MAnagement of Lipoprotein Lipase Deficiency), a 15-year registry focusing on LPLD was launched in 2014 as part of its Risk Management Plan.
  • A total of 11 relevant initiatives/registries were identified (homozygous Familial Hypercholesterolemia (hoFH) [n = 5]; LPLD [n = 1]; Lysosomal Acid Lipase Deficiency [LALD, n = 1], detection of mutations in genetic lipid disorders [n = 4]).

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  • [Copyright] Copyright © 2016. Published by Elsevier B.V.
  • (PMID = 28284702.001).
  • [ISSN] 1879-1484
  • [Journal-full-title] Atherosclerosis
  • [ISO-abbreviation] Atherosclerosis
  • [Language] eng
  • [Publication-type] Journal Article; Review
  • [Publication-country] Ireland
  • [Keywords] NOTNLM ; Alipogene tiparvovec / Familial chylomicronemia syndrome / GENIALL / Gene therapy / Hyperchylomicronemia / Hypertriglyceridemia / Lipoprotein lipase deficiency (LPLD) / Orphan disease / Registry
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5. Atkinson KV, Bishop LA, Rhodes G, Salez N, McEwan NR, Hegarty MJ, Robey J, Harding N, Wetherell S, Lauder RM, Pickup RW, Wilkinson M, Gatherer D: Influenza C in Lancaster, UK, in the winter of 2014-2015. Sci Rep; 2017 Apr 13;7:46578

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Influenza C in Lancaster, UK, in the winter of 2014-2015.
  • We performed nasopharyngeal or nasal swabbing and/or serum sampling (n = 148) in Lancaster, UK, over the winter of 2014-2015.
  • Although we find no evidence that influenza C was a significant respiratory pathogen during the winter of 2014-2015 in Lancaster, we confirm previous observations of seropositivity in the majority of the population. (170 words).

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  • (PMID = 28406194.001).
  • [ISSN] 2045-2322
  • [Journal-full-title] Scientific reports
  • [ISO-abbreviation] Sci Rep
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
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6. Chowell G, Viboud C, Simonsen L, Merler S, Vespignani A: Perspectives on model forecasts of the 2014-2015 Ebola epidemic in West Africa: lessons and the way forward. BMC Med; 2017 Mar 01;15(1):42

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Perspectives on model forecasts of the 2014-2015 Ebola epidemic in West Africa: lessons and the way forward.
  • The unprecedented impact and modeling efforts associated with the 2014-2015 Ebola epidemic in West Africa provides a unique opportunity to document the performances and caveats of forecasting approaches used in near-real time for generating evidence and to guide policy.
  • A number of international academic groups have developed and parameterized mathematical models of disease spread to forecast the trajectory of the outbreak.

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  • (PMID = 28245814.001).
  • [ISSN] 1741-7015
  • [Journal-full-title] BMC medicine
  • [ISO-abbreviation] BMC Med
  • [Language] eng
  • [Publication-type] Editorial
  • [Publication-country] England
  • [Keywords] NOTNLM ; Data sharing / Disease forecast / Ebola / Epidemic model / Exponential growth / Lessons learned / Polynomial growth / Sub-exponential growth / West Africa
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7. Chaillon A, Essat A, Frange P, Smith DM, Delaugerre C, Barin F, Ghosn J, Pialoux G, Robineau O, Rouzioux C, Goujard C, Meyer L, Chaix ML, on behalf the ANRS PRIMO Cohort Study: Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies. Retrovirology; 2017 Feb 21;14(1):15
NCI CPTC Antibody Characterization Program. NCI CPTC Antibody Characterization Program .

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Spatiotemporal dynamics of HIV-1 transmission in France (1999-2014) and impact of targeted prevention strategies.
  • RESULTS: Sociodemographic, geographic, clinical, biological and pol sequence data from 1356 patients were collected between 1999 and 2014.
  • Overall, 387 individuals (28.5%) were involved in clusters: 156 patients (11.5%) in 78 dyads and 231 participants (17%) in 42 larger clusters (median size: 4, range 3-41).
  • Reconstruction of viral migrations across time suggests that Paris area was the major hub of dissemination of both subtype B and CRF02_AG epidemics.

  • Genetic Alliance. consumer health - HIV.
  • MedlinePlus Health Information. consumer health - HIV/AIDS.
  • MedlinePlus Health Information. consumer health - HIV/AIDS in Women.
  • LANL HIV Databases. LANL HIV Databases .
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  • (PMID = 28222757.001).
  • [ISSN] 1742-4690
  • [Journal-full-title] Retrovirology
  • [ISO-abbreviation] Retrovirology
  • [Language] eng
  • [Grant] United States / NIAID NIH HHS / AI / K24 AI100665; United States / NIMH NIH HHS / MH / R01 MH101012; United States / NIDA NIH HHS / DA / R21 DA041007; United States / NIMH NIH HHS / MH / R25 MH081482; United States / NIAID NIH HHS / AI / K23 AI093163; United States / NIAID NIH HHS / AI / R01 AI120009; United States / NIAID NIH HHS / AI / U01 AI068636; United States / NIDA NIH HHS / DA / DP1 DA034978; United States / NIAID NIH HHS / AI / P30 AI027763; United States / NIMH NIH HHS / MH / P30 MH062512; United States / NIAID NIH HHS / AI / P30 AI036214; United States / NIMH NIH HHS / MH / R01 MH097520; United States / NIAID NIH HHS / AI / UM1 AI068636
  • [Publication-type] Journal Article; Multicenter Study
  • [Publication-country] England
  • [Chemical-registry-number] 0 / pol Gene Products, Human Immunodeficiency Virus
  • [Keywords] NOTNLM ; HIV-1 (major topic) / Phylogeography (major topic) / Primary infection (major topic) / Transmission network (major topic) / Treatment as prevention (major topic)
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8. Dela Paz NG, Melchior B, Frangos JA: Shear stress induces Gα&lt;sub&gt;q/11&lt;/sub&gt; activation independently of G protein-coupled receptor activation in endothelial cells. Am J Physiol Cell Physiol; 2017 Apr 01;312(4):C428-C437

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Shear stress induces Gα<sub>q/11</sub> activation independently of G protein-coupled receptor activation in endothelial cells.
  • In this study, we used in situ proximity ligation assay (PLA) to investigate the role of a specific GPCR/Gα<sub>q/11</sub> pair in EC shear stress-induced mechanotransduction.
  • We demonstrated that sphingosine 1-phosphate (S1P) stimulation causes a rapid dissociation at 0.5 min of Gα<sub>q/11</sub> from its receptor S1P<sub>3</sub>, followed by an increased association within 2 min of GPCR kinase-2 (GRK2) and β-arrestin-1/2 with S1P<sub>3</sub> in human coronary artery ECs, which are consistent with GPCR/Gα<sub>q/11</sub> activation and receptor desensitization/internalization.
  • The G protein activator AlF<sub>4</sub> resulted in increased dissociation of Gα<sub>q/11</sub> from S1P<sub>3</sub>, but no increase in association between S1P<sub>3</sub> and either GRK2 or β-arrestin-1/2.
  • Shear stress also caused the rapid activation within 7 s of S1P<sub>3</sub>/Gα<sub>q/11</sub> There were no increased associations between S1P<sub>3</sub> and GRK2 or S1P<sub>3</sub> and β-arrestin-1/2 until 5 min.
  • GDP-β-S, but not VPC23019, prevented dissociation of Gα<sub>q/11</sub> from S1P<sub>3</sub> in response to shear stress.
  • These findings suggest that Gα<sub>q/11</sub> participates in the sensing/transducing of shear stress independently of GPCR activation in ECs.

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  • [Copyright] Copyright 2017 © the American Physiological Society.
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  • (PMID = 28148497.001).
  • [ISSN] 1522-1563
  • [Journal-full-title] American journal of physiology. Cell physiology
  • [ISO-abbreviation] Am. J. Physiol., Cell Physiol.
  • [Language] eng
  • [Grant] United States / NHLBI NIH HHS / HL / R37 HL040696
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; G protein-coupled receptors / endothelial cell / heterotrimeric G proteins / shear stress
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9. Peterson MD, Duchowny K, Meng Q, Wang Y, Chen X, Zhao Y: Low Normalized Grip Strength is a Biomarker for Cardiometabolic Disease and Physical Disabilities Among U.S. and Chinese Adults. J Gerontol A Biol Sci Med Sci; 2017 Mar 10;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • National Health and Nutrition Examination Survey 2011-2012 and 2013-2014 combined surveys (n = 4,544), and the 2011 wave of the China Health and Retirement Longitudinal Study (n = 6,030) were included.
  • Strength was assessed using a handgrip dynamometer, and was normalized to body mass.
  • Results: Every 0.05 lower NGS was independently associated with a 1.49 (95% confidence interval [CI]: 1.42-1.56) and 1.17 (95% CI: 1.11-1.23) odds for diabetes; a 1.46 (95% CI: 1.39-1.53) and 1.11 (95% CI: 1.07-1.15) odds of hyperglycemia; a 1.15 (95% CI: 1.07-1.25) and 1.11 (95% CI: 1.08-1.14) odds of hypertriglyceridemia; a 1.22 (95% CI: 1.17-1.27) and 1.15 (95% CI: 1.12-1.18) odds of low HDL-cholesterol; a 1.19 (95% CI: 1.14-1.24) and 1.10 (95% CI: 1.07-1.14) odds of hypertension; and a 1.36 (95% CI: 1.29-1.42) and 1.10 (95% CI: 1.05-1.15) odds for physical disability status in U.S. and Chinese adults, respectively.

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  • (PMID = 28329157.001).
  • [ISSN] 1758-535X
  • [Journal-full-title] The journals of gerontology. Series A, Biological sciences and medical sciences
  • [ISO-abbreviation] J. Gerontol. A Biol. Sci. Med. Sci.
  • [Language] eng
  • [Grant] United States / NICHD NIH HHS / HD / K01 HD074706
  • [Publication-type] Journal Article
  • [Publication-country] United States
  • [Keywords] NOTNLM ; Aging / Diabetes / Disability / Epidemiology / Muscle weakness
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10. Zhang YX, Wang SR, Chen M, Cheng Y: Recent Trends in Body Mass Index and Waist Circumference among Children and Adolescents in Shandong China. J Trop Pediatr; 2017 Mar 08;

  • [Source] The source of this record is MEDLINE®, a database of the U.S. National Library of Medicine.
  • [Title] Recent Trends in Body Mass Index and Waist Circumference among Children and Adolescents in Shandong China.
  • Background: The present study examined the recent trends in body mass index (BMI) and waist circumference (WC), and the prevalence of general and abdominal obesity among children and adolescents in Shandong, China.
  • Methods: Data for this study were obtained from two cross-sectional surveys of schoolchildren carried out in 2010 and 2014 in Shandong Province, China.
  • Results: For both boys and girls, an increasing trend in BMI and WC was observed between 2010 and 2014 ( p < 0.01), WC has increased faster than BMI.
  • The sum of the prevalence of the three types of obesity increased from 16.63% (boys) and 8.13% (girls) in 2010 to 20.37% (boys) and 11.61% (girls) in 2014 ( p < 0.01).
  • Conclusion: WC and abdominal obesity increased faster than BMI and general obesity among children and adolescents between 2010 and 2014.

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  • (PMID = 28334944.001).
  • [ISSN] 1465-3664
  • [Journal-full-title] Journal of tropical pediatrics
  • [ISO-abbreviation] J. Trop. Pediatr.
  • [Language] eng
  • [Publication-type] Journal Article
  • [Publication-country] England
  • [Keywords] NOTNLM ; abdominal obesity / adolescent / body mass index / general obesity / types of obesity / waist circumference
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